Dr Piccart presents a talk entitled “Tips and tricks in triple-negative breast cancer: how to manage patients in real-life practice?” at the fifth International Breast Cancer Conference, held in Paris, France, on 29 January 2011. Using a real-life case study, at each stage of the patient care pathway from diagnosis through assessment to treatment, the audience are encouraged to vote on potential decisions, before members of an expert panel discuss the evidence and present what they consider constitutes best clinical practice.