Dr Lisa Coussens talks to ecancer at the 2013 NCRI Cancer Conference in Liverpool about inflammation and cancer and how this can be used in the tumour microenvironment.
By studying transgenic mouse models of skin, lung, breast and pancreas cancer development, Dr Coussens lab found that adaptive leukocytes differentially regulate myeloid cell recruitment, activation, and behaviour, by organ-dependent mechanisms.
This has been translated into a recent clinical trial involving triple negative breast cancer.
Read the conference report of the NCRI 2013 meeting for free.