Dr Cornes talks about how Cochrane groups benefit clinicians and discusses the alarming rise in endometrial cancer rates in the last decade. The increase has been attributed to our aging population, lifestyle issues such as obesity and the rise in diabetes/the metabolic syndrome. Dr Cornes talks about the symptoms of endometrial cancer, suggests reasons why these might be overlooked and explains what happens when patients are diagnosed. Dr Cornes explains a number of recent clinical trials investigating radiotherapy: when it is necessary and what the most effective way of administering it is.