Dr Giuseppe Curigliano, speaking at the 2010 ASCO conference: A retrospective study of women with metastatic breast cancer showed that the biological characteristics of their primary tumours - including oestrogen, progesterone, and HER2 status - often changes when the cancer spread to the liver, requiring a change in therapy for many women.
Click here to see an interview with Dr Giuseppe Curigliano on ecancertv from the 11th Milan Breast Cancer Conference 2009.