Removal of alpha/beta T cells and of CD19 B cells in children With acute leukaemia

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Published: 8 Dec 2013
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Dr Alice Bertaina - IRCCS Bambino Gesù Children's Hospital, Rome, Italy

During a press conference at the 2013 ASH Annual Meeting, Dr Alice Bertaina presents data from a recent study on stem cell transplantation.

Transplants of haploidentical, or half-matched, blood-forming stem cells may be an effective option for patients in need of a transplant without a fully matched donor; however, in the past, in comparison to transplant from a fully matched donor, this treatment has been associated with an increased risk of infection and disease recurrence. This study tested the effectiveness of manipulating in the lab these half-matched donor stem cells.