Blood-based test may provide a convenient and effective option for CRC screening in the average-risk U.S. population

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Published: 29 Jan 2025
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Dr Aasma Shaukat - NYU Grossman School of Medicine, New York, USA

Dr Aasma Shaukat speaks to ecancer about the performance of a blood-based test for colorectal cancer screening adjusted to the US census age and sex distribution.

This clinical study validates a new blood-based test for colon cancer screening in adults aged 45 to 85.

Conducted across 200 US centres, participants undergo a colonoscopy and blood sample collection.

The test shows a sensitivity of 79.2% and specificity of 91.5%, effectively detecting colorectal neoplasia in average-risk individuals.

Dr Shaukat says that the next steps involve regulatory submissions and further studies to enhance detection.