Biological ageing measures in clinical assessments can improve treatment in older women with breast cancer

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Published: 1 Nov 2024
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Dr Jingran Ji - The University of California, Los Angeles, USA

Dr Jingran Ji speaks to ecancer about the association of epigenetic age acceleration measures and frailty index in older women with breast cancer.

This study examines the link between epigenetic age and the frailty index in older women with early breast cancer before chemotherapy.

It analyses data from 500 women aged 65 and older, revealing a correlation between biological and functional ageing.

The research employs various epigenetic clocks to assess age acceleration, finding that pre-frail and frail women are biologically older than their robust peers.

The results highlight the potential of biological ageing measures in clinical assessments.