No benefit for adjuvant durvalumab in completely resected NSCLC

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Published: 17 Sep 2024
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Prof Glenwood Goss - University of Ottawa, Ottawa, Canada

Dr Goss talks to ecancer at ESMO 2024 about data he presented from the Canadian Cancer Trials Group BR.31 study.

The trial tested whether there was a benefit to receiving adjuvant durvalumab after complete tumour resection and optional chemotherapy in early-stage (IB-IIIA) non-small cell lung cancer.


The study did not meet its primary endpoint which was targeting a significant improvement in disease free survival in NSCLC patients whose tumours had a tumour cell PD-L1 score of 25% or greater and were EGFR/ALK wildtype.