Neoadjuvant ipilimumab added to nivolumab improves outcomes in resectable advanced melanoma

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Published: 16 Sep 2024
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Dr Minke W. Lucas - The Netherlands Cancer Institute, Amsterdam, Netherlands

Dr Lucas talks to ecancer at ESMO 2024 about data she presented from the phase 3 NADINA trial, looking at immunotherapy in resectable, macroscopic stage III melanoma.

The use of neoadjuvant ipilimumab plus nivolumab in resectable, macroscopic stage III melanoma resulted in improved distant metastasis-free survival and event free survival (EFS) as compared to adjuvant nivolumab.


This EFS-benefit was observed within stage IIIB- and IIIC melanoma.