Dr Monzr Al Malki (City of Hope National Medical Center, Duarte, USA) and Dr Steven Devine (Center for International Blood and Marrow Transplant Research, Minneapolis, USA and Chief Medical Officer of NMDP) talk about post-transplant cyclophosphamide-based graft-versus-host disease prophylaxis following mismatched unrelated donor peripheral blood stem cell transplantation.

In this multi-center phase II study, researchers evaluated the impact of post-transplant cyclophosphamide based graft-versus-host disease prophylaxis on the overall survival of adults and children with advanced haematological malignancies who underwent mismatched unrelated donor transplantation.

Dr Malki discusses the study’s results, which showed success in using mismatched unrelated donors in stem cell transplantation.