SG monotherapy demonstrates a high response rate in PT-ineligible patients with mUC who progressed after CPI therapy

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Published: 6 Mar 2023
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Prof Daniel Petrylak - Yale University Cancer Center, New Haven, USA

Prof Daniel Petrylak speaks to ecancer about the primary analysis of TROPHY-U-01 cohort 2 study which was presented at ASCO GU 2023. TROPHY-U-01 cohort 2 is a phase 2 study of sacituzumab govitecan in platinum-ineligible patients with metastatic urothelial cancer that progressed after prior checkpoint inhibitor therapy. 

The findings of the study found sacituzumab govitecan monotherapy demonstrated a high response rate with an overall manageable safety profile in PT-ineligible patients with mUC who progressed after CPI therapy.

Prof Petrylak concludes by discussing how this could affect the future treatment of urothelial cancer.