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Endoxifen levels in Breast Cancer patients and testing for CYP2D6

SABCS 2008

10 - 14 Dec 2008

Published: 9 Jan 2009

Views: 18147

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Dr John Hawse, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine

Patients receiving tamoxifen therapy who can produce high levels of endoxifen have better survival than those producing low levels - why is this? Test needed for patients with CYP2D6 gene prior to administering tamoxifen

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