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Researchers identified ten ferroptosis-related lncRNAs associated with AML prognosis.
These lncRNAs were used to construct a prognostic model, effectively predicting patient survival.
High-risk patients, identified by the model, exhibited higher mutation rates and immune infiltration compared to low-risk patients.
The study suggests that the model could be useful for personalised treatment and predicting response to immunotherapy.
This research provides valuable insights into the complex interplay between ferroptosis, lncRNAs, and the immune microenvironment in AML.
The identified prognostic model holds promise for improving diagnosis, prognosis, and treatment strategies for AML patients.
The work entitled “A prognostic model for acute myeloid leukaemia based on ferroptosis-related lncRNA and immune infiltration analysis” was published on Biophysics Reports .
Source: Higher Education Press
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